search of a new method for converting anatomical images were engaged neuroscientists at the University of Kyoto, Japan Research and Technology Agency, as well as specialists Research Center RIKEN. This was reported in the scientific journal article, Nature Neuroscience. The new method is called SeeDB.
About enlightenment of human tissue , including the brain, scientists have reflected a long time. Enlightenment is necessary for the study of the whole without dividing it into sections. The main difference between the Japanese and the now well-known method is that the drug is better preserves the anatomical shape of the sample. Furthermore, it is more compatible with lipophilic dyes are used for dyeing preparations preserved with formaldehyde.
Before the start of fructose, scientists held a series of experiments with various solutions. With their help, biologists have tried to change the index of refraction in different parts of the body: the higher the value, the less visible molecules of sugar and fat in the tissues. It was found that the ideal values ??appear using a solution of fructose.
adding a solution of some drugs , blocking the reaction between fructose and substances in the tissues of the body, the researchers conducted an experiment on embryos of mice, as well as on the brains of young and old rodents. After just three days of soaking the samples became transparent.
Image source riken.go.jp
Scientists believe that the use of fructose will examine all the organs of the body. Specifically, of particular interest is the brain. In the bleached state, biologists believe, experts will be able to trace the elements of the chains of neurons. Researchers agree that the coup their method will not, but significantly enhance the ability of scientists.
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