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implanted in animals of the bones of the body, the muscles and cartilage, made the 3D-printer to function normally, according to the findings published in Nature Biotechnology journal the development of American scientists.
breakthrough discovery makes it possible to use living tissue to repair damaged organs.
The doctor-professor from university college London, called the new technology “goose that lays the golden eggs”.
The idea to integrate individual human stem cells in the manufacture of the 3D-printer exact copy of the damaged organ is able to make a revolution in regenerative medicine.
Replace a broken jaw, a damaged heart muscle or to return a person missing an ear with the help of such technology not be easy
today, the main problem of artificially regenerated organs transplantation remains the difficulty of maintaining their viability -. tissue greater than 0.2 mm lack of oxygen and nutrients
Sponge
The team of American Wake Forest medical center has developed a new technique that allows to make using the 3D-printer living tissue penetrated microchannels. The fabric has a sponge-like basis, which allows nutrients and neural networks to penetrate into its structure.
The technology is an integrated system, part of which is responsible for the growth of tissue, the other -. for the production of the 3D-printer replica replaceable body
The starting material consists of a biodegradable plastic, which forms the outer structure of the restored organ, and the gel on water-based, which contains cells and stimulates their growth.
Tests on animals have shown that after the implantation of plastic is gradually destroyed, and its place is taken by a natural structural matrix of proteins produced by the cells.
blood vessels and nerves been grown directly into the implants.
Expanding opportunities
According to professor Anthony Atala, the lead researcher center Wake Forest, at the moment it is already possible to print and human tissue, but scientists want to wait until the end of the tests on animals in order to understand how strong recreated bodies.
whatever it was, 3D-printing opens up new possibilities for medicine. “Suppose we received a patient with an injury of the jaw, a portion of which is not We do patient scans, then transmits the data to the printer, and it will create the missing part of the jawbone, which will be fully fit to the patient.” – He Bi-bi-si said.
Technology, using biodegradable materials, which are then impregnated with a solution of stem cells are already used .
Two years ago, at Wake Forest medical center conducted experiments to transplant the female genital organs grown in the laboratory, but in general, the possibility of such procedures is limited due to problems with preservation of cell viability.
According to professor Atala, in their recent experiment we created a variety of types of tissues – muscles, soft cartilage and hard bones – which indicates the broad capabilities of the new technology
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Professor Martin Birchall, engaged in surgery at university college London, calls the findings striking.
“The prospect of using 3D-printing of human tissues and organs for implantation was real, but I confess, I do not I expect to see such rapid progress. The fact that they managed to create, can be called the goose that lays golden eggs “- admired doctor
He also said that before using new technology on human beings, it is necessary to carry out additional tests, but hopes that it will. Takes a bit of time.
“Given the scale of this breakthrough research, progress in other areas, the resources available to the scientists from Wake Forest and the urgent zdaravoohraneniya needs, I think that in less than a decade, surgeons, such I will be able to do operations with printed organs and tissues. I can not wait “- adds Martin Birchall
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