Tuesday, September 27, 2016

In Mexico a child is born from “three parents” – Slon.ru – Revision of business news

In Mexico successfully conducted a unique operation of artificial insemination in which the child appeared from “three parents”. It is reported by the New Scientist.

fertility embryologists withdrew – from the egg of his mother, who suffers from a rare genetic disease syndrome Leia. This nucleus transplanted into the egg of another woman, and then impregnated her and transferred the embryo back into the mother’s body. The baby was born 6 April 2016. According to doctors, he did not inherit the genetic disease his parents.

Experts have applied the technique of “nuclear transfer spindle” (spindle nuclear transfer), which failed to obtain five embryos, which normally develop only one. In the result, the baby received the nuclear DNA of the mother and the mitochondrial DNA of the female donor. The boy was named Ibrahim Hassan. A team of embryologists from New Hope Fertility Center (new York) conducted the procedure in Mexico, as methods of obtaining embryos from three parents is prohibited in the United States.

Alternative technology that makes possible the conception of three parents, called pronuclear transfer (pronuclear transfer). It involves the fertilization of eggs of the mother and of the female donor with the sperm of the father then extract the nuclei from both eggs before the appearance of the embryo and transfer of the mother nucleus into a donor egg. The first country to permit this technique, the ECO, in 2015 became the UK. This method was not used because of the religious beliefs of the child’s parents.

Mother Ibtisam Shaban, is a carrier of a rare genetic disease affecting the Central nervous system. Disease genes are located in mitochondria and transmitted as part of the mitochondrial DNA to offspring syndrome Leia was the cause of death of the first two children Siobhan. Technology “a child from three parents” allowed the use of mitochondrial DNA from a healthy female donor. According to New Scientist, mutations associated with the disease Leia, have a quarter of the mitochondria of the mother; the unborn child has less than 1% of mutations. The “problem” is the level at which damaged 18% of the mitochondria.

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